منابع مشابه
Choroid Sprouting Assay: An Ex Vivo Model of Microvascular Angiogenesis
Angiogenesis of the microvasculature is central to the etiology of many diseases including proliferative retinopathy, age-related macular degeneration and cancer. A mouse model of microvascular angiogenesis would be very valuable and enable access to a wide range of genetically manipulated tissues that closely approximate small blood vessel growth in vivo. Vascular endothelial cells cultured in...
متن کاملEx Vivo Comparison of the Discoloration Potential of Two Endodontic Sealers in Human Incisors
Background and Aim: Tooth discoloration induced by endodontic materials is a common finding which can impair the aesthetic outcome. The aim of this study was to compare the coronal discoloration induced by Well-Root ST and AH26 root canal sealers by using the Easyshade® colorimeter. Materials and Methods: Forty-five intact maxillary central incisors were involved in this experimental study. Th...
متن کاملHuman Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage
Reliable test systems to identify hepatotoxicity are essential to predict unexpected drug-related liver injury. Here we present a human ex-vivo liver model to investigate acetaminophen-induced liver injury. Human liver tissue was perfused over a 30 hour period with hourly sampling from the perfusate for measurement of general metabolism and clinical parameters. Liver function was assessed by cl...
متن کاملAn Ex-Vivo Study on the Stereoselective Accumulation of Mefloquine Enantiomers in Human Blood Fractions
Mefloquine (MFQ), as a racemic mixture is used for the prophylaxis and treatment of malaria. Stereoselective pharmacodynamic and pharmacokinetic differences have been observed for MFQ. In the present study, the human blood was spiked with racemic MFQ. The concentration of MFQ enantiomers in various blood fractions including packed erythrocyte layer, platelet rich plasma and platelet poor...
متن کاملGnotobiotic Human Colon Ex Vivo
BACKGROUND A novel emulsion with efficacy as an agent for eliminating biofilms was selected. The aim of this study was to examine efficacy and effect of a formulation of ML:8 against commensal bacteria harvested from ex vivo human colonic tissues. METHODS Mucosal sheets, obtained at the time of surgery, were exposed for 2 minutes to one of four solutions: Krebs-Hensleit (KH) solution, saline ...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2017
ISSN: 1755-375X
DOI: 10.1111/j.1755-3768.2017.0t011